Lung function and cardiopulmonary exercise capacity in patients with corrected tetralogy of Fallot.

نویسندگان

  • Gabriel Izbicki
  • Gershon Fink
  • Avi Algom
  • Rafael Hirsch
  • Leonard Blieden
  • Eliezer Klainman
  • Elie Picard
  • Shmuel Goldberg
  • Mordechai R Kramer
چکیده

BACKGROUND Since surgical repair of tetralogy of Fallot was introduced, follow-up studies have shown that the majority of patients lead active lives and have no subjective exercise limitation. OBJECTIVES To examine lung function, cardiopulmonary functional capacity and echo-Doppler assessment of pulmonary pressure in adult patients 20 years after repair of TOF. METHODS Unselected consecutive patients performed full lung function testing, progressive cardiopulmonary exercise, and echo-Doppler assessments of pulmonary pressure. RESULTS Fifty consecutive patients (33 men, 17 women) aged 29 +/- 11 years who underwent surgical repair of TOF at age 10.1 +/- 10.9 years were enrolled. Patients after TOF showed no restriction (forced expiratory vital capacity 80%, total lung capacity 91%) and had normal oxygen saturation (97%) and 6 minute walking distance (600 meters). Echocardiography showed normal pulmonary pressure and left ventricular ejection function (62%). Cardiopulmonary exercise testing showed mild limitation of exercise capacity with oxygen uptake at maximal effort of 75-78% predicted. CONCLUSIONS After corrections of TOF the study patients had normal lung function and pulmonary arterial pressure but mild limitation in their exercise capacity.

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عنوان ژورنال:
  • The Israel Medical Association journal : IMAJ

دوره 10 8-9  شماره 

صفحات  -

تاریخ انتشار 2008